长期以来，科学家一直怀疑男性性功能障碍(ED)与心脏健康有关联。据英国《每日邮报》最新报道，《美国心脏病学会杂志》刊登苏州大学一项新研究确认，ED可能是心脏病的早期信号。
这项涉及近3.7万名男性的12项“ED与心脏病关联研究”的新研究结果显示，与性生活正常的男性相比，ED男子患心脏病危险增加48%，其死亡率也更高。这一危险可能独立于肥胖、吸烟、糖尿病和高血压等常规心血管疾病风险因素。
北京中医药大学东直门医院男科医师王彬告诉生命记者，勃起功能是男性健康的风向标和晴雨表，ED是多种全身疾病的局部表现，可发生于冠心病前2 —3年。
此前，美国梅奥诊所研究发现，改善生活方式有助于缓解ED病情。专家建议，积极锻炼或改善饮食结构(多吃全谷食物、水果蔬菜、坚果和橄榄油)可以将ED病情改善10%。服用他汀类降脂药可使ED改善12%。治疗ED有助于防止或改善心脏病病情。(生物谷 Bioon.com)
doi:10.1016/j.jacc.2011.06.024
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Erectile Dysfunction and Risk of Cardiovascular Disease
Jia-Yi Dong, Yong-Hong Zhang, and Li-Qiang Qin,
Objectives: Our goal was to evaluate the association between erectile dysfunction (ED) and risk of cardiovascular disease (CVD) and all-cause mortality by conducting a meta-analysis of prospective cohort studies. Background: Observational studies suggest an association between ED and the incidence of CVD. However, whether ED is an independent risk factor of CVD remains controversial. Methods: The PubMed database was searched through January 2011 to identify studies that met pre-stated inclusion criteria. Reference lists of retrieved articles were also reviewed. Two authors independently extracted information on the designs of the studies, the characteristics of the study participants, exposure and outcome assessments, and control for potential confounding factors. Either a fixed- or a random-effects model was used to calculate the overall combined risk estimates. Results: Twelve prospective cohort studies involving 36,744 participants were included in the meta-analysis. The overall combined relative risks for men with ED compared with the reference group were 1.48 (95% confidence interval [CI]: 1.25 to 1.74) for CVD, 1.46 (95% CI: 1.31 to 1.63) for coronary heart disease, 1.35 (95% CI: 1.19 to 1.54) for stroke, and 1.19 (95% CI: 1.05 to 1.34) for all-cause mortality. Sensitivity analysis restricted to studies with control for conventional cardiovascular risk factors yielded similar results. No evidence of publication bias was observed. Conclusions: This meta-analysis of prospective cohort studies suggests that ED significantly increases the risk of CVD, coronary heart disease, stroke, and all-cause mortality, and the increase is probably independent of conventional cardiovascular risk factors.
